Proteostasis and neurodegeneration: a closer look at autophagy in Alzheimer's disease
Alzheimer's disease (AD) is characterized by the accumulation of misfolded amyloid-beta and tau proteins. Autophagy acts as a proteostasis process to remove protein clumps, although it progressively weakens with aging and AD, thus facilitating the accumulation of toxic proteins and causing neurodege...
Zapisane w:
| Główni autorzy: | , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Frontiers Media S.A.
2023-11-01
|
| Seria: | Frontiers in Aging Neuroscience |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.frontiersin.org/articles/10.3389/fnagi.2023.1281338/full |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|