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The impact of PrsA over-expression on the Bacillus subtilis transcriptome during fed-batch fermentation of alpha-amylase production

The production of the alpha-amylase (AMY) enzyme in Bacillus subtilis at a high rate leads to the accumulation of unfolded AMY, which causes secretion stress. The over-expression of the PrsA chaperone aids enzyme folding and reduces stress. To identify affected pathways and potential mechanisms invo...

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Detaylı Bibliyografya
Asıl Yazarlar: Adrian S. Geissler, Line D. Poulsen, Nadezhda T. Doncheva, Christian Anthon, Stefan E. Seemann, Enrique González-Tortuero, Anne Breüner, Lars J. Jensen, Carsten Hjort, Jeppe Vinther, Jan Gorodkin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2022-08-01
Seri Bilgileri:Frontiers in Microbiology
Konular:
Online Erişim:https://www.frontiersin.org/articles/10.3389/fmicb.2022.909493/full
Etiketler: Etiketle
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