The repertoire of resistance mutations selected by a Pseudomonas aeruginosa type IV pilus-targeting lytic bacteriophage

ABSTRACT Pseudomonas aeruginosa type IV pili (T4P) are complex surface-exposed nanomachines used for twitching motility and biofilm formation. Exposure to bacteriophages that use T4P as their primary receptor can select for resistance mutations that reduce or abolish pilus expression. Since T4P are...

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Auteurs principaux:	Veronica N. Tran, Hanjeong Harvey, Tanisha S. Lahane, Lori L. Burrows
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology 2026-05-01
Collection:	mBio
Sujets:	bacteriophages bacteriophage therapy Pseudomonas aeruginosa type IV pili antibiotic resistance type II secretion
Accès en ligne:	https://journals.asm.org/doi/10.1128/mbio.00243-26
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