Glucose-Raising Polymorphisms in the Human Clock Gene Cryptochrome 2 (CRY2) Affect Hepatic Lipid Content.

Circadian rhythms govern vital functions. Their disruption provokes metabolic imbalance favouring obesity and type-2 diabetes. The aim of the study was to assess the role of clock genes in human prediabetes. To this end, genotype-phenotype associations of 121 common single nucleotide polymorphisms (...

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Главные авторы:	Fausto Machicao, Andreas Peter, Jürgen Machann, Ingmar Königsrainer, Anja Böhm, Stefan Zoltan Lutz, Martin Heni, Andreas Fritsche, Fritz Schick, Alfred Königsrainer, Norbert Stefan, Hans-Ulrich Häring, Harald Staiger
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Public Library of Science (PLoS) 2016-01-01
Серии:	PLoS ONE
Online-ссылка:	http://europepmc.org/articles/PMC4699770?pdf=render
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