Common genetic variation in the SERPINF1 locus determines overall adiposity, obesity-related insulin resistance, and circulating leptin levels.

<h4>Objective</h4>Pigment epithelium-derived factor (PEDF) belongs to the serpin family of peptidase inhibitors (serpin F1) and is among the most abundant glycoproteins secreted by adipocytes. In vitro and mouse in vivo data revealed PEDF as a candidate mediator of obesity-induced insulin resistance...

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מידע ביבליוגרפי

Principais autores:	Anja Böhm, Anna-Maria Ordelheide, Jürgen Machann, Martin Heni, Caroline Ketterer, Fausto Machicao, Fritz Schick, Norbert Stefan, Andreas Fritsche, Hans-Ulrich Häring, Harald Staiger
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Public Library of Science (PLoS) 2012-01-01
סדרה:	PLoS ONE
גישה מקוונת:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0034035&type=printable
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