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The Recombinant Maize Ribosome-Inactivating Protein Transiently Reduces Viral Load in SHIV89.6 Infected Chinese Rhesus Macaques

Ribosome inactivating proteins (RIPs) inhibit protein synthesis by depurinating the large ribosomal RNA and some are found to possess anti-human immunodeficiency virus (HIV) activity. Maize ribosome inactivating protein (RIP) has an internal inactivation loop which is proteolytically removed for ful...

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Auteurs principaux: Rui-Rui Wang, Ka-Yee Au, Hong-Yi Zheng, Liang-Min Gao, Xuan Zhang, Rong-Hua Luo, Sue Ka-Yee Law, Amanda Nga-Sze Mak, Kam-Bo Wong, Ming-Xu Zhang, Wei Pang, Gao-Hong Zhang, Pang-Chui Shaw, Yong-Tang Zheng
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2015-01-01
Collection:Toxins
Sujets:
maize RIP
anti-HIV
animal model
viral load
Accès en ligne:http://www.mdpi.com/2072-6651/7/1/156
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