Protection from inflammatory organ damage in a murine model of hemophagocytic lymphohistiocytosis using treatment with IL-18 binding protein

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition due to the association of an infectious agent with lymphocyte cytotoxicity defects, either of congenital genetic origin in children or presumably acquired in adults. In HLH patients, an excess of lymphocyte or macrophage cytoki...

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Detalhes bibliográficos

Principais autores:	Laura eChiossone, Sandra eAudonnet, Bruno eChetaille, Lionel eChasson, Catherine eFarnarier, Yael eBerda-Haddad, Stefan eJordan, Ulrich eKoszinowski, Marc eDalod, Karin eMazodier, Daniela eNovick, Charles eDinarello, Eric eVivier, Gilles eKaplanski
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2012-08-01
coleção:	Frontiers in Immunology
Assuntos:	natural killer (NK) cells Hemophagocytic lymphohistiocytosis (HLH) IL-18 IL-18 binding protein (IL-18BP) Macrophage Activation Syndrome (MAS)
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00239/full
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