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MANUFACTURING NATURAL KILLER CELLS AS MEDICINAL PRODUCTS

Natural Killer (NK) cells are Innate Lymphoid Cells (ILC) with cytotoxic and regulatory properties. Their functions are tightly regulated by an array of inhibitory and activating receptors, and their mechanisms of activation strongly differ from antigen recognition in the context of HLA presentation...

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Principais autores: Christian CHABANNON, Bechara MFARREJ, Sophie GUIA DA SILVA, Sophie UGOLINI, Raynier DEVILLIER, Didier BLAISE, Eric Vivier, Boris CALMELS
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016-11-01
coleção:Frontiers in Immunology
Assuntos:
Natural Killer cells ; Innate Lymphoid Cells ; Immunotherapy ; Immuno-oncology ; Cellular therapy; Cell transplant ; Manufacturing
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00504/full
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