Hutchinson-Gilford progeria syndrome alters the endothelial genetic response to laminar shear stress
IntroductionHutchinson-Gilford Progeria Syndrome (HGPS) is a fatal, accelerated-aging disease caused by a mutation in the nuclear envelope protein Lamin A. The resulting mutant protein, progerin, accumulates on the nuclear envelope, causing nuclear blebbing, altered gene expression, and other cellul...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
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Frontiers Media S.A.
2026-02-01
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| Collection: | Frontiers in Physiology |
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| Accès en ligne: | https://www.frontiersin.org/articles/10.3389/fphys.2025.1599339/full |
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