Characterization of EpCAM in thyroid cancer biology by three-dimensional spheroids in vitro model

Abstract Background Thyroid cancer (TC) is the most common endocrine malignancy. Nowadays, undifferentiated thyroid cancers (UTCs) are still lethal, mostly due to the insurgence of therapy resistance and disease relapse. These events are believed to be caused by a subpopulation of cancer cells with...

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Hlavní autoři:	Viola Ghiandai, Elisa Stellaria Grassi, Giacomo Gazzano, Laura Fugazzola, Luca Persani
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-06-01
Edice:	Cancer Cell International
Témata:	Thyroid cancer Tumor-initiating cells EpCAM Spheroid cultures Regulated intramembrane proteolysis Drug resistance
On-line přístup:	https://doi.org/10.1186/s12935-024-03378-2
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