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Mechanisms of mitochondrial dysfunction in premature ovarian insufficiency

Abstract Premature ovarian insufficiency (POI) is a clinical syndrome characterized by the decline of ovarian function in women under the age of 40, and its core pathological feature is the irreversible depletion of the ovarian reserve. Mitochondria serve as the central hub for energy metabolism and...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Chenyu Jia, Huihui Li, Ruotong Ju, Puhua Zhang, Li Peng, Tingting Xue, Xinyu Zhu, Shu Wang, Jiali Luo, Ruixiang Zhu, Xuan Jing, Xiangrong Cui
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2026-06-01
Schriftenreihe:Journal of Ovarian Research
Schlagworte:
Premature ovarian insufficiency
Mitochondrial dysfunction
Follicular atresia
Granulosa cell death
Online-Zugang:https://doi.org/10.1186/s13048-026-02170-2
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