Mechanisms of mitochondrial dysfunction in premature ovarian insufficiency

Abstract Premature ovarian insufficiency (POI) is a clinical syndrome characterized by the decline of ovarian function in women under the age of 40, and its core pathological feature is the irreversible depletion of the ovarian reserve. Mitochondria serve as the central hub for energy metabolism and...

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Hlavní autoři:	Chenyu Jia, Huihui Li, Ruotong Ju, Puhua Zhang, Li Peng, Tingting Xue, Xinyu Zhu, Shu Wang, Jiali Luo, Ruixiang Zhu, Xuan Jing, Xiangrong Cui
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2026-06-01
Edice:	Journal of Ovarian Research
Témata:	Premature ovarian insufficiency Mitochondrial dysfunction Follicular atresia Granulosa cell death
On-line přístup:	https://doi.org/10.1186/s13048-026-02170-2
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