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RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy

ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying inflammation‐mediated fibrosis in skeletal muscle remain inadequately understood. This study revealed a molecular link between macrophages and...

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Principais autores: Pengkai Wu, Zehua Zhang, Kai Zheng, Ziqi Zhu, Yong Zhu, Abdukahar Kiram, Lei Zhao, Huihui Chen, Zhu Xu, Xihua Li, Beicheng Sun, Zhijian Li, Dengqiu Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2026-03-01
coleção:Advanced Science
Assuntos:
FAPs
fibrosis
macrophages
muscular dystrophy
RUNX2
Acesso em linha:https://doi.org/10.1002/advs.202510850
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