Detection and Functional Evaluation of the P2X7 Receptor in hiPSC Derived Neurons and Microglia-Like Cells

A large body of evidence suggests the involvement of the ATP-gated purinergic receptor P2X7 (P2X7R) in neurodegenerative diseases, including Alzheimer’s disease. While it is well-described to be present and functional on microglia cells contributing to inflammatory responses, some reports suggest a...

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Hlavní autoři:	Linda Francistiová, Kinga Vörös, Zsófia Lovász, András Dinnyés, Julianna Kobolák
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-01-01
Edice:	Frontiers in Molecular Neuroscience
Témata:	P2X7 receptor induced pluripotent stem cell neuron microglia Alzheimer’s disease
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fnmol.2021.793769/full
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