Downregulation of RCN1 promotes pyroptosis in acute myeloid leukemia cells

Reticulocalbin‐1 (RCN1) is expressed aberrantly and at a high level in various tumors, including acute myeloid leukemia (AML), yet its impact on AML remains unclear. In this study, we demonstrate that RCN1 knockdown significantly suppresses the viability of bone marrow mononuclear cells (BMMNCs) fro...

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Autori principali:	Sisi Deng, Yuming Pan, Na An, Fengyi Chen, Huan Chen, Heng Wang, Xiaojing Xu, Rui Liu, Linlin Yang, Xiaomei Wang, Xin Du, Qiaoxia Zhang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2023-12-01
Serie:	Molecular Oncology
Soggetti:	AML caspase‐1 GSDMD IFN‐1 pyroptosis RCN1
Accesso online:	https://doi.org/10.1002/1878-0261.13521
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