Downregulation of RCN1 promotes pyroptosis in acute myeloid leukemia cells

Reticulocalbin‐1 (RCN1) is expressed aberrantly and at a high level in various tumors, including acute myeloid leukemia (AML), yet its impact on AML remains unclear. In this study, we demonstrate that RCN1 knockdown significantly suppresses the viability of bone marrow mononuclear cells (BMMNCs) fro...

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Detalhes bibliográficos

Principais autores:	Sisi Deng, Yuming Pan, Na An, Fengyi Chen, Huan Chen, Heng Wang, Xiaojing Xu, Rui Liu, Linlin Yang, Xiaomei Wang, Xin Du, Qiaoxia Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2023-12-01
coleção:	Molecular Oncology
Assuntos:	AML caspase‐1 GSDMD IFN‐1 pyroptosis RCN1
Acesso em linha:	https://doi.org/10.1002/1878-0261.13521
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