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microRNA-mediated regulation of microRNA machinery controls cell fate decisions

microRNAs associate with Argonaute proteins, forming the microRNA-induced silencing complex (miRISC), to repress target gene expression post-transcriptionally. Although microRNAs are critical regulators in mammalian cell differentiation, our understanding of how microRNA machinery, such as the miRIS...

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Autori principali: Qiuying Liu, Mariah K Novak, Rachel M Pepin, Taylor Eich, Wenqian Hu
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2021-10-01
Serie:eLife
Soggetti:
mir-182
mir-183
Ago2
RISC
let-7 microrma
pluripotency
Accesso online:https://elifesciences.org/articles/72289
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