Lin41/Trim71 is essential for mouse development and specifically expressed in postnatal ependymal cells of the brain.

Lin41/Trim71 is a heterochronic gene encoding a member of the Trim-NHL protein family, and is the original, genetically defined target of the microRNA let-7 in C. elegans. Both the LIN41 protein and multiple regulatory microRNA binding sites in the 3’ UTR of the messenger RNA (mRNA) are highly conse...

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Principais autores:	Elisa eCuevas, Agnieszka eRybak-Wolf, Anna Maria Rohde, Duong Thi Thuy Nguyen, F Gregory eWulczyn
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2015-04-01
coleção:	Frontiers in Cell and Developmental Biology
Assuntos:	Ependyma adult neural stem cells gene trapping Lin41 Trim71
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00020/full
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