Prokineticin Receptor Inhibition With PC1 Protects Mouse Primary Sensory Neurons From Neurotoxic Effects of Chemotherapeutic Drugs in vitro

Neurotoxicity is a common side effect of chemotherapeutics that often leads to the development of chemotherapy-induced peripheral neuropathy (CIPN). The peptide Prokineticin 2 (PK2) has a key role in experimental models of CIPN and can be considered an insult-inducible endangering mediator. Since pr...

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Principais autores:	Giorgia Moschetti, Theodora Kalpachidou, Giada Amodeo, Roberta Lattanzi, Paola Sacerdote, Michaela Kress, Silvia Franchi
格式:	Artigo
語言:	Inglês
出版:	Frontiers Media S.A. 2020-09-01
叢編:	Frontiers in Immunology
主題:	chemotherapy DRG neurons prokineticins neurotoxicity
在線閱讀:	https://www.frontiersin.org/article/10.3389/fimmu.2020.02119/full
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