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Prokineticin System Is a Pharmacological Target to Counteract Pain and Its Comorbid Mood Alterations in an Osteoarthritis Murine Model

Osteoarthritis (OA) is the most prevalent joint disease associated with chronic pain. OA pain is often accompanied by mood disorders. We addressed the role of the Prokineticin (PK) system in pain and mood alterations in a mice OA model induced with monosodium iodoacetate (MIA). The effect of a PK an...

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Principais autores: Giulia Galimberti, Giada Amodeo, Giulia Magni, Benedetta Riboldi, Gianfranco Balboni, Valentina Onnis, Stefania Ceruti, Paola Sacerdote, Silvia Franchi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-09-01
coleção:Cells
Assuntos:
prokineticins
osteoarthritis pain
neuroinflammation
anxiety
depression
Acesso em linha:https://www.mdpi.com/2073-4409/12/18/2255
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