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Mode of administration influences plasma levels of active Centella asiatica compounds in 5xFAD mice while markers of neuroinflammation remain unaltered

IntroductionA water extract of Centella asiatica (L.) Urban [Apiaceae] (CAW) has demonstrated cognitive-enhancing effects in mouse models of Alzheimer’s disease and aging, the magnitude of which is influenced by whether CAW is delivered in the drinking water or the diet. These cognitive benefits are...

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Bibliografiske detaljer
Principais autores: Alex B. Speers, Kirsten M. Wright, Mikah S. Brandes, Nareg Kedjejian, Donald G. Matthews, Maya Caruso, Christopher J. Harris, Seiji Koike, Thuan Nguyen, Joseph F. Quinn, Amala Soumyanath, Nora E. Gray
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-03-01
Serier:Frontiers in Neuroscience
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Online adgang:https://www.frontiersin.org/articles/10.3389/fnins.2024.1277626/full
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