Mode of administration influences plasma levels of active Centella asiatica compounds in 5xFAD mice while markers of neuroinflammation remain unaltered

IntroductionA water extract of Centella asiatica (L.) Urban [Apiaceae] (CAW) has demonstrated cognitive-enhancing effects in mouse models of Alzheimer’s disease and aging, the magnitude of which is influenced by whether CAW is delivered in the drinking water or the diet. These cognitive benefits are...

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मुख्य लेखकों:	Alex B. Speers, Kirsten M. Wright, Mikah S. Brandes, Nareg Kedjejian, Donald G. Matthews, Maya Caruso, Christopher J. Harris, Seiji Koike, Thuan Nguyen, Joseph F. Quinn, Amala Soumyanath, Nora E. Gray
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Frontiers Media S.A. 2024-03-01
श्रृंखला:	Frontiers in Neuroscience
विषय:	Centella asiatica Alzheimer’s disease neuroinflammation 5xFAD triterpenes caffeoylquinic acids
ऑनलाइन पहुंच:	https://www.frontiersin.org/articles/10.3389/fnins.2024.1277626/full
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