Inhibition of the hERG Potassium Channel by a Methanesulphonate-Free E-4031 Analogue
<i>hERG</i> (<i>human Ether-à-go-go Related Gene</i>)-encoded potassium channels underlie the cardiac rapid delayed rectifier (I<sub>Kr</sub>) potassium current, which is a major target for antiarrhythmic agents and diverse non-cardiac drugs linked to the drug-induced form of long QT syndrome. E-403...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI AG
2023-08-01
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| Series: | Pharmaceuticals |
| Assuntos: | |
| Acceso en liña: | https://www.mdpi.com/1424-8247/16/9/1204 |
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