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Inhibition of the hERG Potassium Channel by a Methanesulphonate-Free E-4031 Analogue

<i>hERG</i> (<i>human Ether-à-go-go Related Gene</i>)-encoded potassium channels underlie the cardiac rapid delayed rectifier (I<sub>Kr</sub>) potassium current, which is a major target for antiarrhythmic agents and diverse non-cardiac drugs linked to the drug-induced form of long QT syndrome. E-403...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Matthew V. Helliwell, Yihong Zhang, Aziza El Harchi, Christopher E. Dempsey, Jules C. Hancox
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2023-08-01
Saila:Pharmaceuticals
Gaiak:
Sarrera elektronikoa:https://www.mdpi.com/1424-8247/16/9/1204
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