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Using machine learning models to predict the impact of template mismatches on polymerase chain reaction assay performance

Abstract Molecular assays are critical tools for the diagnosis of infectious diseases. These assays have been extremely valuable during the COVID pandemic, used to guide both patient management and infection control strategies. Sustained transmission and unhindered proliferation of the virus during...

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Principais autores: Brittany Knight, Taylor Otwell, Michael P. Coryell, Jennifer Stone, Phillip Davis, Bryan Necciai, Paul E. Carlson, Shanmuga Sozhamannan, Alyxandria M. Schubert, Yi H. Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-05-01
Colecção:Scientific Reports
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Acesso em linha:https://doi.org/10.1038/s41598-025-98444-8
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