Using machine learning models to predict the impact of template mismatches on polymerase chain reaction assay performance

Abstract Molecular assays are critical tools for the diagnosis of infectious diseases. These assays have been extremely valuable during the COVID pandemic, used to guide both patient management and infection control strategies. Sustained transmission and unhindered proliferation of the virus during...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Brittany Knight, Taylor Otwell, Michael P. Coryell, Jennifer Stone, Phillip Davis, Bryan Necciai, Paul E. Carlson, Shanmuga Sozhamannan, Alyxandria M. Schubert, Yi H. Yan
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Nature Portfolio 2025-05-01
श्रृंखला:	Scientific Reports
विषय:	Signature erosion qPCR performance In silico prediction False negative result Supervised learning
ऑनलाइन पहुंच:	https://doi.org/10.1038/s41598-025-98444-8
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