α-Synuclein oligomers form by secondary nucleation
Abstract Oligomeric species arising during the aggregation of α-synuclein are implicated as a major source of toxicity in Parkinson’s disease, and thus a major potential drug target. However, both their mechanism of formation and role in aggregation are largely unresolved. Here we show that, at phys...
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| Huvudupphov: | , , , , , , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Nature Portfolio
2024-08-01
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| Serie: | Nature Communications |
| Länkar: | https://doi.org/10.1038/s41467-024-50692-4 |
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