Renal tubular epithelial cell-derived Exosomal miR-330-3p plays a key role in fibroblast activation and renal fibrosis by regulating CREBBP

Abstract Background Renal tubular injury and activation of peripheral fibroblasts are hallmarks of chronic kidney disease (CKD), suggesting a close connection between the two cell types. Exosomes transport miRNAs and other substances to recipient cells. The involvement of exosome-mediated intercellu...

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Detalhes bibliográficos

Principais autores:	Rong Dai, Meng Cheng, Chu-Yi Peng, Ze-Ping Cao, Hua Jin, Dong Wang, Yi-Ping Wang, Lei Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-04-01
Colecção:	Stem Cell Research & Therapy
Assuntos:	Renal fibrosis Exosome Renal tubular epithelial cell Fibroblast MicroRNA
Acesso em linha:	https://doi.org/10.1186/s13287-025-04338-x
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