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TRABD maintains mitochondrial homeostasis and protects against ischemia reperfusion-induced renal tubular injury

Mitochondria serve as hubs for many critical cellular processes, and their functions and dynamics are tightly controlled. TRABD is a Tiki/TraB family protein with unknown function. Here, we characterized TRABD as a novel outer mitochondrial membrane protein. Depletion of TRABD in cells severely impa...

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Principais autores: Wenqi Duan, Wenye Wu, Cui Yang, Mei Zhang, Xuemei Li, Wenmin Tian, Yang Chen, Xinjun Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-07-01
coleção:Frontiers in Cell and Developmental Biology
Assuntos:
TRABD
mitochondrial membrane protein
dynamics
mitophagy
PGAM5
ischemia reperfusion-induced renal tubular injury
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcell.2025.1619339/full
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