Nascent Induced Pluripotent Stem Cells Efficiently Generate Entirely iPSC-Derived Mice while Expressing Differentiation-Associated Genes

The ability of induced pluripotent stem cells (iPSCs) to differentiate into all adult cell types makes them attractive for research and regenerative medicine; however, it remains unknown when and how this capacity is established. We characterized the acquisition of developmental pluripotency in a su...

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Detalhes bibliográficos

Principais autores:	Bhishma Amlani, Yiyuan Liu, Taotao Chen, Ly-Sha Ee, Peter Lopez, Adriana Heguy, Effie Apostolou, Sang Yong Kim, Matthias Stadtfeld
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2018-01-01
coleção:	Cell Reports
Assuntos:	reprogramming iPSCs pluripotency developmental potential tetraploid complementation Otx2
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124717319356
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