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Slice of Life: Porcine Kidney Slices for Testing Antifibrotic Drugs in a Transplant Setting

Circulatory death donor (DCD) kidneys are increasingly used to enlarge the donor pool. These kidneys undergo ischemia-reperfusion injury, frequently leading to renal fibrosis. Transforming growth factor beta 1 (TGF-β1) and matrix metalloproteases have been identified as central mediators of fibrosis...

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Bibliográfalaš dieđut
Váldodahkkit: L. Leonie van Leeuwen, Mitchel J. R. Ruigrok, Henri G. D. Leuvenink, Peter Olinga
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2023-04-01
Ráidu:Transplantology
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Liŋkkat:https://www.mdpi.com/2673-3943/4/2/7
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