Improved Expression of Aggregation-Prone Tau Proteins Using a Spidroin-Derived Solubility Tag

Tauopathies, a group of neurodegenerative disorders, are characterized by the abnormal aggregation of microtubule-associated Tau proteins in neurons and glial cells. The process of Tau proteins transitioning from soluble, intrinsically disordered monomers to disease-associated aggregates is still un...

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Bibliografische Detailangaben

Hauptverfasser:	Kevin Muwonge, Bedri Yaman, Attila Mészáros, Giorgio Russo, Alexander Volkov, Peter Tompa
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2024-06-01
Schriftenreihe:	Separations
Schlagworte:	solubility tag spider silk protein aggregation-prone recombinant protein expression protein purification tauopathies
Online-Zugang:	https://www.mdpi.com/2297-8739/11/7/198
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