Early-Life Rotenone Exposure Enhances Nigrostriatal Vulnerability and Parkinsonian Neurodegeneration in Aging Rats

Environmental exposure to neurotoxicants during critical developmental windows may program long-term susceptibility to neurodegenerative diseases such as Parkinson’s disease. Here, we investigated whether rotenone exposure during neurodevelopment induces a more severe Parkinsonian phenotype during a...

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Principais autores:	Margarita Gómez-Chavarín, Rocio Morales-Gómez, Juan Ramón Padilla-Mendoza, Patricia Padilla, Ismael Torres-Saldaña, Patricia Vergara-Aragón, Maria-del-Carmen Silva-Lucero, Nuria Galindo-Solano
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2026-05-01
Serija:	Toxics
Teme:	rotenone neurodevelopment medium spiny neurons dopaminergic neurons senescence Parkinson’s disease
Online dostop:	https://www.mdpi.com/2305-6304/14/6/470
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