Trophoblast cell surface antigen 2 (TROP2) from ascitic extracellular vesicles drives peritoneal metastasis of ovarian cancer by mesothelial-to-mesenchymal transition

Abstract Background Ovarian cancer (OvCA) exhibits a distinctive tendency toward peritoneal metastasis, a pathological process that greatly affects disease progression and postoperative recurrence. Understanding the biological mechanisms underlying this metastatic cascade is critical for improving p...

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Detalhes bibliográficos

Principais autores:	Guangyan Xie, Guanfeng Chen, Wenqiang Lv, Wei Tai, Bei Zhang, Xueyan Zhou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-11-01
coleção:	Journal of Ovarian Research
Assuntos:	Ovarian cancer TROP2 Extracellular vesicles Peritoneal metastasis Mesothelial-to-mesenchymal transition
Acesso em linha:	https://doi.org/10.1186/s13048-025-01845-6
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