The cGAS-STING pathway in senescence and aging-related diseases: mechanisms and therapeutic opportunities
Abstract The cGAS-STING pathway acts as a critical molecular hub connecting genomic instability with cellular senescence. Functioning as a key regulator of the innate immune system, this pathway detects aberrant cytoplasmic DNA to activate downstream inflammatory responses, thereby playing a pivotal...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BMC
2026-04-01
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| Serija: | Cell Communication and Signaling |
| Teme: | |
| Online pristup: | https://doi.org/10.1186/s12964-026-02855-7 |
| Oznake: |
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