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CXCR4-tropic HIV-1 infection in an immunocompetent monkey model

Abstract Current animal models of HIV-1 infection are either immunocompromised or rely on proxy viruses instead of HIV-1. Here, we establish an immunocompetent animal model for CXCR4-tropic HIV-1 in owl monkeys (Aotus nancymaae). Through analysis of 191 owl monkeys, genetic characterization and func...

Deskribapen osoa

Gorde:
Egile Nagusiak: Nicholas R. Meyerson, Vanessa L. Bauer, Will T. Fattor, Cody J. Warren, Arturo Barbachano-Guerrero, Melisa J. Weiss, Obaiah Dirasantha, Bridget L. Burris, Adetunji S. Adesina, Joseph L. Timpona, Emily R. Feldman, Ryan T. Fahy, Paul Gendler, Ava Fainberg, Pramod N. Nehete, Kathryn A. Shelton, Analy Galvan, George W. Tustin, Paul J. Koehle, Maria D. Salinas, Omar Davila, Elizabeth I. Lindemann, Sean E. Clark, Mackenzie L. Garnett, C. Todd DeMarco, Salvatore R. Scianna, Thomas N. Denny, Jens H. Kuhn, Pyone P. Aye, Ron S. Veazey, Sarah M. Kezar, Gregory K. Wilkerson, Sara L. Sawyer
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2026-03-01
Saila:Nature Communications
Sarrera elektronikoa:https://doi.org/10.1038/s41467-026-70209-5
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