CXCR4-tropic HIV-1 infection in an immunocompetent monkey model

Abstract Current animal models of HIV-1 infection are either immunocompromised or rely on proxy viruses instead of HIV-1. Here, we establish an immunocompetent animal model for CXCR4-tropic HIV-1 in owl monkeys (Aotus nancymaae). Through analysis of 191 owl monkeys, genetic characterization and func...

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Principais autores:	Nicholas R. Meyerson, Vanessa L. Bauer, Will T. Fattor, Cody J. Warren, Arturo Barbachano-Guerrero, Melisa J. Weiss, Obaiah Dirasantha, Bridget L. Burris, Adetunji S. Adesina, Joseph L. Timpona, Emily R. Feldman, Ryan T. Fahy, Paul Gendler, Ava Fainberg, Pramod N. Nehete, Kathryn A. Shelton, Analy Galvan, George W. Tustin, Paul J. Koehle, Maria D. Salinas, Omar Davila, Elizabeth I. Lindemann, Sean E. Clark, Mackenzie L. Garnett, C. Todd DeMarco, Salvatore R. Scianna, Thomas N. Denny, Jens H. Kuhn, Pyone P. Aye, Ron S. Veazey, Sarah M. Kezar, Gregory K. Wilkerson, Sara L. Sawyer
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2026-03-01
Series:	Nature Communications
Acceso en liña:	https://doi.org/10.1038/s41467-026-70209-5
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