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Widespread use of non-productive alternative splice sites in Saccharomyces cerevisiae.

Saccharomyces cerevisiae has been used as a model system to investigate the mechanisms of pre-mRNA splicing but only a few examples of alternative splice site usage have been described in this organism. Using RNA-Seq analysis of nonsense-mediated mRNA decay (NMD) mutant strains, we show that many S....

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Principais autores: Tadashi Kawashima, Stephen Douglass, Jason Gabunilas, Matteo Pellegrini, Guillaume F Chanfreau
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Genetics
Acceso en liña:http://europepmc.org/articles/PMC3983031?pdf=render
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