QR Kod

Exploring the inhibitory mechanism of resorcinylic isoxazole amine NVP-AUY922 towards the discovery of potential heat shock protein 90 (Hsp90) inhibitors

Heat shock protein 90 (Hsp90) is an ATP-dependant molecular chaperone that facilitates protein maturation while protecting cancer cells from temperature-induced stress. Hsp90, therefore, remains an attractive target for anticancer drug development. The study aimed to use multidimensional computation...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Ayanda M. Magwenyane, Monsurat M. Lawal, Daniel G. Amoako, Anou M. Somboro, Clement Agoni, Rene B. Khan, NdumisoN. Mhlongo, Hezekiel M. Kumalo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2022-03-01
Seri Bilgileri:Scientific African
Konular:
Pharmacophore-based virtual screening
Molecular docking
Molecular dynamics
ONIOM method
Hsp90 N-terminal
NVP-AUY922
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2468227622000163
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller