Biodegradable nanotherapeutic with simultaneously GSH depletion and H2O2 supplying for enhanced synergistic chemotherapy/chemodynamic therapy

Chemodynamic therapy (CDT) has been exploited as an emerging therapeutic modality for cancer treatment. However, insufficient intracellular H2O2 levels and ultrahigh glutathione (GSH) in the tumor microenvironment (TME) severely restrict CDT efficacy. To address these concerns, in this work, a self-...

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Autors principals:	Rui Hou, Tianxiang Lu, Jiayuan Sun, Dong Li, Liang Xu, Ruhong Zhang, Zheyuan Yu
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2023-11-01
Col·lecció:	Materials & Design
Matèries:	Chemodynamic therapy Tumor microenvironment Glucose oxidase Biodegradable GSH depletion
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0264127523008298
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