Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects

Abstract Thyroid hormone (TH) is a thermogenic activator with anti-obesity potential. However, systemic TH administration has no obvious clinical benefits on weight reduction. Herein we selectively delivered triiodothyronine (T3) to adipose tissues by encapsulating T3 in liposomes modified with an a...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Kang Chen, Lai Yee Cheong, Yuan Gao, Yaming Zhang, Tianshi Feng, Qin Wang, Leigang Jin, Eric Honoré, Karen S. L. Lam, Weiping Wang, Xiaoyan Hui, Aimin Xu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2022-12-01
Schriftenreihe:	Nature Communications
Online-Zugang:	https://doi.org/10.1038/s41467-022-35470-4
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!