Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects

Abstract Thyroid hormone (TH) is a thermogenic activator with anti-obesity potential. However, systemic TH administration has no obvious clinical benefits on weight reduction. Herein we selectively delivered triiodothyronine (T3) to adipose tissues by encapsulating T3 in liposomes modified with an a...

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Hlavní autoři:	Kang Chen, Lai Yee Cheong, Yuan Gao, Yaming Zhang, Tianshi Feng, Qin Wang, Leigang Jin, Eric Honoré, Karen S. L. Lam, Weiping Wang, Xiaoyan Hui, Aimin Xu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2022-12-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-022-35470-4
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