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Neuroprotective actions of 2,4-dinitrophenol: Friend or foe?

Abstract 2,4-dinitrophenol (DNP) has long been known to be toxic at high concentrations, an effect related to uncoupling of mitochondrial oxidative phosphorylation. Five years ago, however, we reported that low concentrations of DNP protect neurons against the toxicity of the amyloid-b peptide. Sinc...

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Bibliografische gegevens
Hoofdauteurs: Sérgio Teixeira Ferreira, Fernanda Guarino De Felice
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
Reeks:Dementia & Neuropsychologia
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Online toegang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642007000400334&lng=en&tlng=en
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