LncRNA UCA1 promotes keratinocyte-driven inflammation via suppressing METTL14 and activating the HIF-1α/NF-κB axis in psoriasis

Abstract Keratinocytes are closely associated with innate immunity and inflammatory responses, and are dysregulated during the development of psoriasis, but the underlying mechanisms are not yet fully understood. This work aims to reveal the effects of long non-coding RNA (lncRNA) UCA1 in psoriatic...

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Hlavní autoři:	Yibo Hu, Li Lei, Ling Jiang, Hongliang Zeng, Yushan Zhang, Chuhan Fu, Haoran Guo, Yumeng Dong, Yujie Ouyang, Xiaolin Zhang, Jinhua Huang, Qinghai Zeng, Jing Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 2023-04-01
Edice:	Cell Death and Disease
On-line přístup:	https://doi.org/10.1038/s41419-023-05790-4
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