Deciphering a missing piece of the branched-chain amino acids uptake puzzle: YhjE is an L-isoleucine and L-valine transporter in Escherichia coli K-12

Branched-chain amino acid (BCAA) uptake in bacteria underpins fitness, pathogenesis, and industrial strain performance, yet the transport landscape, even in Escherichia coli, remains incomplete. Here, we identify and characterize YhjE as a BCAA permease specific for L-isoleucine and L-valine. Select...

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Ngā kaituhi matua:	Sergey V. Molev, Agnessa A. Stepanova, Tatiana V. Vybornaya, Andrey A. Khozov, Makar M. Surkov, Gennadii A. Badun, Maria G. Chernysheva, Alexander I. Netrusov, Alexander S. Yanenko, Sergey P. Sineoky, Dmitrii M. Bubnov
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Frontiers Media S.A. 2025-12-01
Rangatū:	Frontiers in Microbiology
Ngā marau:	Escherichia coli L-isoleucine uptake L-valine uptake transmembrane transport amino acid transporter
Urunga tuihono:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1727951/full
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