ISO-upregulated BECN1 specifically promotes LC3B-dependent autophagy and anticancer activity in invasive bladder cancer

Isorhapontigenin (ISO), an active compound isolated from the Chinese herb Gnetum Cleistostachyum, exhibited strong preventive and therapeutic effects on bladder cancer (BC) both in vitro and in vivo. Our previous studies revealed that ISO-induced autophagy is crucial for its anti-cancer activity. Ho...

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Detalhes bibliográficos

Principais autores:	Xiaohui Hua, Daimin Xiang, Jiheng Xu, Shouyue Zhang, Shuai Wu, Zhongxian Tian, Junlan Zhu, Chuanshu Huang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-01-01
Colecção:	Translational Oncology
Assuntos:	Isorhapontigenin (ISO) LC3B autophagy BECN1 NCL
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S1936523324003048
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