The effects of 17α-estradiol treatment on endocrine system revealed by single-nucleus transcriptomic sequencing of hypothalamus

This study investigated 17α-estradiol’s effects on aged hypothalamic physiological activity via long-term administration. Single-nucleus transcriptomic sequencing (snRNA-seq) was performed on pooled hypothalami from each group: aged male Norway brown rats treated with 17α-estradiol (O.T), aged contr...

Descripción completa

Detalles Bibliográficos

Autores principales:	Lei Li, Guanghao Wu, Xiaolei Xu, Junling Yang, Lirong Yi, Ziqing Yang, Zheng Mo, Li Xing, Ying Shan, Zhuo Yu, Yinchuan Li
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	eLife Sciences Publications Ltd 2025-09-01
Colección:	eLife
Materias:	hypothalamus 17α-estradiol snRNA-seq Gnrh Crh Oxt
Acceso en línea:	https://elifesciences.org/articles/100346
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!