IL-4-mediated monocyte differentiation modulates CD163 expression and PRRSV infection

Host immune status critically influences susceptibility to viral infections; however, the impact of cytokine-driven innate immune differentiation on viral permissiveness remains poorly understood. Here, we investigated whether IL-4-mediated monocyte differentiation modulates porcine reproductive and...

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Hlavní autoři:	Narae Kim, Young-Jun Ju, Yoon-Chul Kye, Cheol Gyun Kim, Young Jin Pyung, Da-Jeong Park, Sun-Jong You, Hakhyun Ka, Seung Hyun Han, Cheol-Heui Yun
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-06-01
Edice:	Frontiers in Microbiology
Témata:	CD163 CD8+ T cell interleukin-4 (IL-4) monocyte derived cell (MDC) porcine reproductive and respiratory syndrome virus (PRRSV)
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fmicb.2026.1817131/full
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