Modeling pediatric low-grade glioma heterogeneity using human forebrain organoids

Abstract Pediatric low-grade gliomas (pLGGs) are the most common type of brain tumors in children, characterized by their typically slow growth and oncogene-induced senescence. Preclinical models provide the opportunity to investigate the effects of various treatments in a controlled setting before...

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Autors principals:	Gloria Leva, Lucia Santomaso, Matteo Gianesello, Sara Patrizi, Federica Ress, Federico Cocchini, Celeste Antonacci, Francesca Gianno, Luana Abballe, Chiara Lago, Noemi Pozza, Gabriele Trentini, Marina Cardano, Simone Minasi, Francesca Romana Buttarelli, Manila Antonelli, Davide Pernici, Linda Petrucci, Francesco Antonica, Emma Busarello, Martina Iannuzzi, Alessia Soldano, Toma Tebaldi, Evelina Miele, Elisabetta Ferretti, Luca Tiberi
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2026-04-01
Col·lecció:	Molecular Cancer
Accés en línia:	https://doi.org/10.1186/s12943-026-02612-x
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