Longitudinal high-frequency blood biomarkers of axonal injury and astrocytic activation after immune reconstitution in multiple sclerosis

Abstract Background Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) reflect axonal damage and astrocytic injury. Their clinical role in longitudinal real-world monitoring after immune reconstitution therapy (IRT) in multiple sclerosis (MS) remains insufficiently de...

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Bibliographic Details

Main Authors:	Hernan Inojosa, Luise Werder, Rocco Haase, Undine Proschmann, Pascal Benkert, Jens Kuhle, Hagen B Huttner, Tjalf Ziemssen, Katja Akgün
Format:	Artigo
Language:	Inglês
Published:	BMC 2025-12-01
Series:	Journal of Neuroinflammation
Subjects:	Neurofilament light chain Glial fibrillary acidic protein Multiple sclerosis Immune reconstitution therapy Disease monitoring
Online Access:	https://doi.org/10.1186/s12974-025-03674-2
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